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ADCON®-L: a review of its development, mechanism of action, and preclinical data

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Abstract

ADCON®-L Anti-Adhesion Barrier Gel is a resorbable gel that is placed into the site of a laminectomy before surgical closure and acts as a barrier to scar and surgical adhesions. The scientific rationale for ADCON products is based on certain properties of glial cells and the nature and role of the basal lamina. ADCON-L was evaluated in laminectomy models using rats and rabbits and a discectomy model in dogs. In all studies, ADCON-L was an effective barrier to peridural scar and surgical adhesions.

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Authors and Affiliations

  1. Gliatech Inc., 23420 Commerce Park Road, 44122, Cleveland, Ohio, USA

    R. C. A. Frederickson

Authors
  1. R. C. A. Frederickson
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This study was supported by Gilatech Inc.

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Frederickson, R.C.A. ADCON®-L: a review of its development, mechanism of action, and preclinical data. Eur Spine J 5, S7–S9 (1996). https://doi.org/10.1007/BF00298566

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  • DOI: https://doi.org/10.1007/BF00298566

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