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Changes in serum carboxyterminal telopeptide of type I collagen in an experimental model of canine osteomyelitis

  • Orthopedic Surgical Forum
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Abstract

Blood biochemical indices of bone turnover were followed up for 1 month in six dogs with experimental osteomyelitis. The bone infection resulted in significant increase in parameters of bone formation (serum bone alkaline phosphatase and serum osteocalcin) and bone resorption [serum carboxyterminal telopeptide of type I collagen (i-ICTP)] as early as the end of the second week after the operation and inoculation. There was strong evidence that serum i-ICTP levels could be useful for the early diagnosis of postoperative complications in veterinary orthopedics, such as posttraumatic osteomyelitis.

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Authors and Affiliations

  1. Department of Surgery, Faculty of Veterinary Medicine, 6000, Stara Zagora, Bulgaria

    J. P. Philipov, M. D. Pascalev, B. Y. Aminkov & C. D. Grosev

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  1. J. P. Philipov
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  2. M. D. Pascalev
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  3. B. Y. Aminkov
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  4. C. D. Grosev
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Philipov, J.P., Pascalev, M.D., Aminkov, B.Y. et al. Changes in serum carboxyterminal telopeptide of type I collagen in an experimental model of canine osteomyelitis. Calcif Tissue Int 57, 152–154 (1995). https://doi.org/10.1007/BF00298436

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  • DOI: https://doi.org/10.1007/BF00298436

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