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Placental alkaline phosphatase polymorphism in some Italian populations

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Summary

Gene frequencies of Pl alleles for alkaline phosphatase of human placenta have been studied in the populations of Rome and L'Aquila. The latter represents a mixed sample of descendants from ancient Italic populations which in the last 20 centuries have been free from significant immigratory influx.

The Pl gene frequencies in the two Italian populations are significantly different, the Pls 1 frequency being lower and Plf 1 frequency higher in the population of L'Aquila as compared to the population of Rome. The gene frequency of the 3 common Pl alleles in the population of Rome are quite similar to that found in some Northern-European populations. The frequency of the Pls 1 allele observed in the population of L'Aquila is the lowest (and correspondingly that for Plf 1 allele is the highest) amongst all populations studied so far.

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Authors and Affiliations

  1. Evolutionary Genetics Center of National Research Council, Department of Genetics (Faculty of Science), University of Rome, Rome, Italy

    E. Bottini, P. Lucarelli, R. Palmarino, G. F. Spennati & G. Reynaud

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  1. E. Bottini
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  2. P. Lucarelli
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  3. R. Palmarino
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  4. G. F. Spennati
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  5. G. Reynaud
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Bottini, E., Lucarelli, P., Palmarino, R. et al. Placental alkaline phosphatase polymorphism in some Italian populations. Hum Genet 11, 62–65 (1970). https://doi.org/10.1007/BF00296305

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  • DOI: https://doi.org/10.1007/BF00296305

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