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Sex chromatin frequency in buccal mucosal tissue: The distribution of single, double and triple sex chromatin bodies

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Summary

A method of recording sex chromatin scores with a reproducibility of ±3% at two standard deviations is used to investigate the incidence of sex chromatin bodies in normal and polysomic-X individuals. The distribution of sex chromatin bodies in nuclei from both groups may be expressed by a single simple distribution function. The form of the function suggests that the condensation of all X chromosomes (normal and abnormal nuclei) is a random process occurring within a limited period of the cell cycle.

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Authors and Affiliations

  1. Department of Genetics, University of Sheffield, Sheffield

    Diana J. Curtis

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  1. Diana J. Curtis
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Supported by a postgraduate research grant from the Science Research Council. This work forms part of a thesis submitted in partial fulfillment of the requirements for the degree of Master of Science, University of Sheffield.

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Curtis, D.J. Sex chromatin frequency in buccal mucosal tissue: The distribution of single, double and triple sex chromatin bodies. Hum Genet 11, 22–28 (1970). https://doi.org/10.1007/BF00296300

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  • DOI: https://doi.org/10.1007/BF00296300

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