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Non-random association of human acrocentric chromosomes

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Summary

The association of human acrocentric chromosomes was found to be nonrandom using fluorescence technic.

The occurrence of chromosomes D13-15 in Robertsonian rearrangement has been shown to be non-random (Hecht et al., 1968). Ohno et al. (1961) have postulated these rearrangements might be related to acrocentric association. In two studies (Nakagame, 1969; Shaw et al., 1969), however, a random distribution of the D group chromosomes in association was found by autoradiography in lymphocytes. The recently described fluorescence technic (Caspersson et al., 1971) permits a reliable identification of each of the 23 pairs and we would like to report the results of our re-examination of acrocentric association by this method.

Zusammenfassung

Die Assoziation menschlicher akrozentrischer Chromosomen hat sich als nicht zufällig erwiesen. Es wurde die Fluorescenztechnik benutzt.

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References

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Authors and Affiliations

  1. Department of Pediatrics, University of Colorado Medical Center, Denver, Colorado, USA

    Shivanand R. Patil & Herbert A. Lubs

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  1. Shivanand R. Patil
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  2. Herbert A. Lubs
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Patil, S.R., Lubs, H.A. Non-random association of human acrocentric chromosomes. Humangenetik 13, 157–159 (1971). https://doi.org/10.1007/BF00295797

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  • DOI: https://doi.org/10.1007/BF00295797

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