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Genetic polymorphism of C′3 (β1C-globulin) component of complement in a German and a Spanish population

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Summary

The polymorphism of the major component of human complement (C′3 or \(\beta _{1^C }\)-globulin) at that time is interpreted formally by the genetic model “5 codominant alleles at one autosomal locus”. Examination of this hypothesis has been performed examinating a sample of 482 unrelated persons in the two populations, 71 families with 127 children and 115 mother/child combinations in a German population. It could be stated that 4 alleles or more are involved in this polymorphism.

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Authors and Affiliations

  1. Institute of Human Genetics, University of Hamburg, Germany

    H. Werner Goedde, Heide-G. Benkmann & Ludwig Hirth

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  1. H. Werner Goedde
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  2. Heide-G. Benkmann
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  3. Ludwig Hirth
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Goedde, H.W., Benkmann, HG. & Hirth, L. Genetic polymorphism of C′3 (β1C-globulin) component of complement in a German and a Spanish population. Hum Genet 10, 231–234 (1970). https://doi.org/10.1007/BF00295785

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  • DOI: https://doi.org/10.1007/BF00295785

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