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Utilization of 11β-hydroxysteroids by the salivary gland ducts

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Summary

Parotid, submandibular and sublingual glands were removed from rats and investigated histochemically. Pyruvate oxidase, iso-citric dehydrogenase, α-ketoglutarate oxidase, succinic dehydrogenase, malate dehydrogenase and furfuryl alcohol dehydrogenase activity were observed in the salivary ducts which may be interpreted as significant of high metabolic activity.

The 11 β-hydroxysteroid dehydrogenase in these ducts displayed marked substrate specificity utilizing 11β-hydroxyandrostenedione and cortisol but not 11 β-hydroxyoestrone or 11 β-hydroxyprogesterone. The relationship between corticosteroids and salivary electrolyte concentrations is discussed.

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  1. Department of Anatomy, The University, W. 2., Glasgow, Scotland

    M. M. Ferguson

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  1. M. M. Ferguson
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Ferguson, M.M. Utilization of 11β-hydroxysteroids by the salivary gland ducts. Histochemie 9, 269–274 (1967). https://doi.org/10.1007/BF00294394

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