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Efficient DNA pairing in a Neurospora mutant defective in chromosome pairing

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Summary

A Neurospora crassa mutation, mei-2, affecting recombination and pairing of homologous chromosomes during meiosis, was characterized for its effect on repeat-induced point mutation (RIP). We found that RIP, which depends on recognition of DNA sequence homology, is not inhibited by mei-2, suggesting that the defect in chromosome pairing of this mutant is not due to a defect in DNA pairing and that DNA pairing is not dependent on chromosome pairing.

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Authors and Affiliations

  1. Institute of Molecular Biology, University of Oregon, 97403, Eugene, OR, USA

    Henriette M. Foss & Eric U. Selker

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  1. Henriette M. Foss
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  2. Eric U. Selker
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Communicated by B. Kilbey

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Foss, H.M., Selker, E.U. Efficient DNA pairing in a Neurospora mutant defective in chromosome pairing. Molec. Gen. Genet. 231, 49–52 (1991). https://doi.org/10.1007/BF00293820

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  • DOI: https://doi.org/10.1007/BF00293820

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