, Volume 76, Issue 2, pp 111–122 | Cite as

Heteromorphism for chromosome 1, a requirement for normal development in crested newts

  • Herbert C. Macgregor
  • Heather Horner


In all adult males and females of T. cristatus most of the long arm of chromosome 1 is achiasmate and heteromorphic with respect to Giemsa C-staining pattern. This heteromorphism correlates well with the heteromorphism seen by previous investigators on the lampbrush chromosomes of adult females. The heteromorphism has nothing to do with sex determination. All those fertile eggs of T. cristatus that develop normally beyond blastula are capable of development through to late tail-bud stage, but 50% of them arrest at late tail-bud and ultimately die. Homomorphism for the long arm of chromosome 1 can only be found in those embryos that arrest at late tailbud. The same findings apply to T. marmoratus, which also shows heteromorphism for chromosome 1, but not to T. alpestris, which has homomorphic chromosomes 1 and a potential 100% developmental success rate.


Success Rate Developmental Biology Adult Male Adult Female Normal Development 
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  1. Barsacchi, G., Bussotti, L., Mancino, G.: The maps of the lampbrush chromosomes of Triturus (Amphibia, Urodela). IV. Triturus vulgaris meridionalis. Chromosoma (Berl.) 31, 255–279 (1970)Google Scholar
  2. Callan, H.G., Lloyd, L.: Lampbrush chromosomes of crested newts Triturus cristatus (Laurenti). Phil. Trans. roy. Soc. Lond., 243 B, 135–219 (1960)Google Scholar
  3. Callan, H.G., Lloyd, L.: Working maps of the lampbrush chromosomes of Amphibia. In: Handbook of genetics, Vol. 4 (R.C. King, ed.), p. 57–77. New York: Plenum Publishing Corporation 1975Google Scholar
  4. Callan, H.G., Spurway, H.: A study of meiosis in interracial hybrids of the newt, Triturus cristatus. J. Genet. 50, 235–249 (1951)Google Scholar
  5. Kezer, J., Sessions, S.K.: Chromosomes variation in the plethodontid salamander Aneides ferreus. Chromosoma (Berl.) 71, 65–80 (1979)Google Scholar
  6. Macgregor, H.C.: In situ hybridization of highly repetitive DNA to chromosomes of Triturus cristatus. Chromosoma (Berl.) 71, 57–64 (1979)Google Scholar
  7. Macgregor, H.C., Andrews, C.: The arrangement and expression of “middle repetitive” DNA sequences on lampbrush chromosomes of Triturus. Chromosoma (Berl.) 63, 109–126 (1977)Google Scholar
  8. Macgregor, H.C., Jones, C.: Chromosomes, DNA sequences, and evolution in salamanders of the genus Aneides. Chromosoma (Berl.) 63, 1–9 (1977)Google Scholar
  9. Mancino, G., Barsacchi, G.: The maps of the lampbrush chromosomes of Triturus (Amphibia, Urodela). II. Triturus helveticus. Riv. Biol. 59, 339–351 (1966)Google Scholar
  10. Mancino, G., Barsacchi, G.: The maps of the lampbrush chromosomes of Triturus (Amphibia, Urodela). III. Triturus italicus. Ann. Embryol. Morphogen. 2, 355–377 (1969)Google Scholar
  11. Mancino, G., Nardi, I., Ragghianti, M.: Lampbrush chromosomes from semi albino crested newts, Triturus cristatus carnifex (Laurenti). Experientia (Basel) 28, 856–860 (1972)Google Scholar
  12. Mancino, G., Ragghianti, M., Bucci-Innocenti, S.: I cariotipi di Triturus marmoratus e T. cristatus studiati con il “C-staining method”. Atti Accad. naz. Lincei Rc. (Roma) 55, 559–564 (1973)Google Scholar
  13. Mancino, G., Ragghianti, M., Bucci-Innocenti, S.: Cytotaxonomy and cytogenetics in European newt species. In: The reproductive biology of Amphibians (D.H. Taylor and S.I. Guttman, eds.), pp. 411–447. New York, London: Plenum Publishing Corporation 1977Google Scholar
  14. Morgan, G.T.: Absence of chiasmata from the heteromorphic region of chromosome 1 during spermatogenesis in Triturus cristatus carnifex. Chromosoma (Berl.) 66, 269–280 (1978)Google Scholar
  15. Nardi, I., Ragghianti, M., Mancino, G.: Characterization of the lampbrush chromosomes of the marbled newt Triturus marmoratus (Latreille, 1800). Chromosoma (Berl.) 37, 1–22 (1972)Google Scholar
  16. Nieuwkoop, P.D., Faber, J. (eds.): Normal Table of Xenopus laevis (Daudin). Amsterdam: North Holland Publishing Company 1967Google Scholar
  17. Old, R.W., Callan, H.G., Gross, K.W.: Localization of histone gene transcripts in newt lampbrush chromosomes by in situ hybridization. J. Cell Sci. 27, 57–79 (1977)Google Scholar
  18. Rudak, E., Callan, H.G.: Differential staining and chromatin packing of the mitotic chromosomes of the newt Triturus cristatus. Chromosoma (Berl.) 56, 49–362 (1976)Google Scholar
  19. Schmid, M., Olert, J., Klett, C.: Chromosome banding in Amphibia. III. Sex chromosomes in Triturus. Chromosoma (Berl.) 71, 29–55 (1979)Google Scholar
  20. Sumner, A.T.: A simple technique for demonstrating centromeric heterochromatin. Exp. Cell Res. 75, 304–306 (1972)Google Scholar
  21. Varley, J.M., Macgregor, H.C., Nardi, I., Andrews, C.: Transcription of highly repeated DNA sequences during the lampbrush stage in Triturus cristatus carnifex. Chromosoma (Berl.) (in press, 1980)Google Scholar
  22. White, M.J.D.: The spermatogenesis of hybrids between Triturus cristatus and T. marmoratus (Urodela). J. exp. Zool. 102, 179–207 (1946)Google Scholar
  23. Wickbom, T.: Cytological studies on Dipnoi, Urodela, Anura, and Emys. Hereditas (Lund) 31, 241–345 (1945)Google Scholar

Copyright information

© Springer-Verlag 1980

Authors and Affiliations

  • Herbert C. Macgregor
    • 1
  • Heather Horner
    • 1
  1. 1.Department of ZoologySchool of Biological Sciences, University of LeicesterLeicesterEngland

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