Abstract
Noninvasive isotope chelate methods to assess glomerular filtration rate (GFR) are less accurate than blood sampling. However, some measurement errors would be expected to be constant for an individual, and repeat estimations may be less variable. In 18 patients, estimates of GFR were obtained by 2 gamma camera techniques and a portable external detector at a mean interval of 1 year, to assess accuracy in predicting a change of GFR. Errors in these techniques were not significantly better than those predicted from two independent estimates. Most GFR measurement error for noninvasive methods appears to be random.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Brochner-Mortensen (1972) A simple method for the determination of GFR. Scand J Clin Lab Invest 30:271–274
Corrigan DM, Collis SA (1984) Estimation of GFR without blood samples during renography. Clin Phys Physiol Meas 5:279–284
Fleming JS, Keast CM, Waller DG, Ackery DM (1987) Measurement of glomerular filtration rate with 99mTc DTPA: a comparison of gamma camera methods. Eur J Nucl Med 13:250–253
Gates GF (1982) Glomerular filtration rate: estimation from fractional renal accumulation of 99mTc DTPA (stannous). Am J Radiol 138:565–570
Lee TY, Constable AR, Cranage RW (1982) A method for GFR determination without blood samples in routine renal scintigraphy with 99mTc DTPA. In: Joeckes AM, Cosntable AR, Brown NJG, Tauxe WN (eds) Radionuclides in nephrology. Academic Press, London, pp 107–112
Russel CD, Bischoft PG, Kontzen FN, Rowell KL, Yester MV, Lloyd LK, Tauxe WN, Dubovsky EV (1985) Measurement of GFR using 99mTc DTPA and gamma camera: a comparison of methods. Eur J Nucl Med 10:519–521
Waller DG, Keast CM, Fleming JS, Ackery DM (1987) Measurement of glomerular filtration rate with 99mTc DTPA: a comparison of plasma clearance methods. J Nucl Med 28:372–377
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Waller, D.G., Ramsay, B., Fleming, J.S. et al. Longitudinal assessment of glomerular filtration rate by gamma camera and portable external detector. Eur J Nucl Med 13, 402–403 (1987). https://doi.org/10.1007/BF00292491
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00292491