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Meiosis in Sxr male mice

II. Further absence of cytological evidence for a Y-autosome rearrangement in sex-reversed (Sxr) mice

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Abstract

If the sex-reversal factor (Sxr) in mice is represented by a segment of the Y chromosome translocated on to an autosome, this segment might be expected to show some evidence of attempted pairing with the normal Y chromosome at the first meiotic division. Our failure to find such evidence in a light microscope study of the silver-stained pachytene spermatocytes from Sxr/+, XY males further supports existing cytological information that the factor is more likely to be represented by an autosomal dominant gene mutation.

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Evans, E.P., Burtenshaw, M.D. & Brown, B.B. Meiosis in Sxr male mice. Chromosoma 81, 19–26 (1980). https://doi.org/10.1007/BF00292420

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  • DOI: https://doi.org/10.1007/BF00292420

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