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Beobachtung eines Faktorenaustausches zwischen den Blutgruppen-Genorten MN und Ss

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Abstract

In a family, in the first instance investigated in a linkage study, blood grouping showed MNSs distributions which could not be expected by inheritance of complexes MS, Ms, NS, and Ns, as generally assumed. (father: MS/Ns, mother: MS/Ns or Ms/NS, first child: MS/NS, second child: Ns/Ns). Since illegitimacy of one or both of the children could be excluded practically with certainty, only a mutation at the MN or Ss locus, or a crossing-over between the MN and the Ss locus can explain the children's genotypes, the crossing-over being the most probably right interpretation of MNSs findings in this family.

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Authors and Affiliations

  1. Institut für Humangenetik der Universität Düsseldorf, Düsseldorf, Deutschland

    Walter Scholz

  2. Kinderpoliklinik der Universität München, München, Deutschland

    Jan-Dieter Murken

Authors
  1. Walter Scholz
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  2. Jan-Dieter Murken
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Mit Unterstützung durch die Deutsche Forschungsgemeinschaft.

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Scholz, W., Murken, JD. Beobachtung eines Faktorenaustausches zwischen den Blutgruppen-Genorten MN und Ss. Hum Genet 4, 268–273 (1967). https://doi.org/10.1007/BF00292199

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  • DOI: https://doi.org/10.1007/BF00292199

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