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C3 and Bf complement types in chronic renal failure

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Summary

C3 and BF allele frequencies were studied in 55 patients with idiopathic membranous nephropathy (IMN) and unrelated normal individuals from North-East England. Eighteen of these IMN patients progressed to renal failure and C3*S allele showed a significant increase in these patients. A possible mechanism for this increase is briefly discussed.

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Papiha, S.S., Rodger, R.S.C. C3 and Bf complement types in chronic renal failure. Hum Genet 72, 260–261 (1986). https://doi.org/10.1007/BF00291891

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  • DOI: https://doi.org/10.1007/BF00291891

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