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The tyrosinase-positive oculocutaneous albinism locus is not linked to the β-globin locus in man

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Summary

Twenty informative families have been studied, and linkage between the tyrosinase-positive oculocutaneous albinism locus and the β-globin locus has been excluded with a maximum lod score of -9.85 at θ=0.05. In lower mammals there is linkage between the p locus (considered to be equivalent to the human tyrosinase-positive oculocutaneous albinism) and the β-globin locus.

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Authors and Affiliations

  1. MRC Human Ecogenetics Research Unit, Department of Human Genetics, School of Pathology, South African Institute for Medical Research University of the Witwatersrand, P.O. Box 1038, Johannesburg, South Africa

    R. A. Heim, D. S. Dunn, S. E. Candy, E. Zwane, J. G. R. Kromberg & T. Jenkins

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  1. R. A. Heim
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  2. D. S. Dunn
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  3. S. E. Candy
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  4. E. Zwane
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  5. J. G. R. Kromberg
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  6. T. Jenkins
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Heim, R.A., Dunn, D.S., Candy, S.E. et al. The tyrosinase-positive oculocutaneous albinism locus is not linked to the β-globin locus in man. Hum Genet 79, 89 (1988). https://doi.org/10.1007/BF00291719

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  • DOI: https://doi.org/10.1007/BF00291719

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