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Familial occurrence of severe ulnar aplasia and lobster claw feet: A new syndrome

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Summary

In this paper we describe a previously unreported association of ulnar defect and lobster-claw deformity of the feet, occurring in four males belonging to two generations of the same family. Minor expression of the same ulnar reduction defect in female relatives suggests X-linked recessive inheritance, but an autosomal dominant with irregular expression cannot be excluded.

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Authors and Affiliations

  1. Division of Medical Genetics, Department of Human Biology, University of Leuven, B-3000, Leuven, Belgium

    H. van den Berghe & J. P. Fryns

  2. Division of Rhumatology, University Hospital Sint Barbara, Leuven, Belgium

    J. Dequeker

Authors
  1. H. van den Berghe
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  2. J. Dequeker
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  3. J. P. Fryns
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  4. G. David
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Aspirant N.F.W.O.

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van den Berghe, H., Dequeker, J., Fryns, J.P. et al. Familial occurrence of severe ulnar aplasia and lobster claw feet: A new syndrome. Hum Genet 42, 109–113 (1978). https://doi.org/10.1007/BF00291633

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  • DOI: https://doi.org/10.1007/BF00291633

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