Summary
The distribution of the adenylate kinase groups was studied on blood samples obtained from 2270 Swiss individuals. The distribution was found to be in excellent agreement with the Hardy-Weinberg equilibrium. The obtained gene frequencies were similar to those observed in other Caucasian populations (AK1=0.957, AK2=0.043). In 335 mother/childpairs no theoretically “impossible” combinations were found. No significant difference was observed between the gene-frequencies of men and women. Among the blood samples investigated an “unusual” phenotype was found in one mother and her child.
References
Bowman, J. E., Frischer, H., Ajmar, F., Carson, P. E., Gower, M. K.: Population, family and biochemical investigation of human adenylate kinase polymorphism. nature 214, 1156–1158 (1967).
Fildes, R. A., Harris, H.: Genetically determined variation of adenylate kinase in man. Nature 209, 261–263 (1966).
Modiano, G., Scozzari, R., Gigliani, F., Filippi, G., Latte, B.: Studies on red cell phosphoglucomutase and adenylate kinase polymorphisms in Sardinia. Acc. Naz. Linc. 42, 906–915 (1967).
Rapley, S., Robson, E. B., Harris, H., Smith, S. M.: Data on the incidence, segregation and linkage relations of the adenylate kinase (AK) polymorphism. Ann. hum. Genet. 31, 237–242 (1967).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Pflugshaupt, R., Scherz, R. & Bütler, R. The adnylate kinase (AK)-groups in the Swiss population. Hum Genet 12, 167–169 (1971). https://doi.org/10.1007/BF00291473
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00291473