Summary
Starch-gel electrophoresis for adenylate kinase (AK) was performed on 2519 haemolysates from 6 population samples of unrelated males in Finland, 4 Finnish Lapp populations, the Maris (Cheremisses) in the USSR, and an Eskimo population in NW Greenland. Between the Finland Swedes and Finns no significant difference in AK polymorphism was observed and the allele frequency estimates of AK were comparable with those found in other Europeans. The indigenous “pure” Skolt Lapps showed absence of the AK2 gene, which was also extremely low in the Fisher and Mountain Lapps. All the Lapp populations so far studied show an extremely low frequency of the AK2 gene. The rarity of AK2 in Lapps may offer a better approach to the estimation of intermixture than certain other genes which vary in frequency in different Lapp populations. Among the Maris AK2 frequencies are lower (0.017) than among other Europeans. The AK2 was also very low (0.016) in the Greenland Eskimo population on Augpilagtok Island.
The results obtained for the AK phenotypes in 149 Lapp families and in 84 mothers and their children are in agreement with the hypothesis that AK1 and AK2 are alleles at one and the same autosomal locus. The present family and mother-child studies add further evidence for the acceptance of the AK system as a valuable tool in cases of disputed paternity.
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Supported by the Finnish National Research Council for Medical Sciences, the Finnish Academy of Science and Letters, the Wenner-Gren Foundation for Anthropological Research and the Deutsche Forschungsgemeinschaft. Preparations were partly obtained as a gift from Boehringer GmbH, Mannheim, Germany.
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Eriksson, A.W., Fellman, J., Kirjarinta, M. et al. Adenylate kinase polymorphism in populations in Finland (Swedes, Finns, Lapps), in Maris, and in Greenland Eskimos. Hum Genet 12, 123–130 (1971). https://doi.org/10.1007/BF00291467
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DOI: https://doi.org/10.1007/BF00291467