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10q(q23→qter) duplication: GOTs, HK1, and other gene markers

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Summary

Gene marker analyses have been carried out in a patient with 10q(q23→qter) duplication. The observed elevation of red cell glutamic oxaloacetic transaminase activity is compatible with earlier somatic cell hybridization studies that mapped the locus to this region. Hexokinase-1 activity in the red cells was normal, which is consistent with its prior assignment to the unaffected part of chromosome 10 (10pter→q23).

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References

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Authors and Affiliations

  1. Division of Medical Genetics, Department of Medicine, UCLA Center for the Health Sciences, 90024, Los Angeles, CA, USA

    Robert S. Sparkes & Maryellen C. Sparkes

  2. Division of Medical Genetics, Department of Pediatrics, UCLA Center for the Health Sciences, 90024, Los Angeles, CA, USA

    Robert S. Sparkes

  3. Department of Psychiatry, UCLA Center for the Health Sciences, 90024, Los Angeles, CA, USA

    Robert S. Sparkes & Maryellen C. Sparkes

  4. Department of Pediatrics (Genetics), Kaiser-Permanente Medical Center, 91402, Panorama City, CA, USA

    Harold N. Bass

Authors
  1. Robert S. Sparkes
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  2. Harold N. Bass
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  3. Maryellen C. Sparkes
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Sparkes, R.S., Bass, H.N. & Sparkes, M.C. 10q(q23→qter) duplication: GOTs, HK1, and other gene markers. Hum Genet 42, 267–270 (1978). https://doi.org/10.1007/BF00291306

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  • DOI: https://doi.org/10.1007/BF00291306

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