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Archives of Microbiology

, Volume 155, Issue 1, pp 99–102 | Cite as

Effect of aminoglycoside antibiotics on the autolytic enzyme of Streptomyces griseus

  • István Szabó
  • András Penyige
  • György Barabás
  • Judit Barabás
Original Papers

Abstract

The isolated cell wall of Streptomyces griseus 52–1 strain labelled with fluorescein isothiocyanate (FITC) and containing wall-bound autolytic enzyme was lysed as a function of different cations. The autolysis was accelerated by aminoglycoside antibiotics (streptomycin and the structurally closely related neomycin) which have a polycationic character. Since this strain is a streptomycin producer it is suggested that streptomycin may have a regulatory function on autolysis.

Key words

Autolysis Amidase enzyme Role of aminoglycosides Streptomyces griseus 

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References

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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • István Szabó
    • 1
  • András Penyige
    • 1
  • György Barabás
    • 1
  • Judit Barabás
    • 1
  1. 1.Institute of BiologyUniversity Medical SchoolDebrecenHungary

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