Abstract
Thirty-four (4.1%) out of 820 patients operated for colorectal cancer between April 1989 and October 1992 were found to have synchronous cancers. Twenty (59%) were male and 14 (41%) were female. The mean age was 69.3 years (range=25 to 89 yr). Synchronous tumours were located in the same or adjacent segments of the large intestine in 24 (71%) of the patients. A curative resection was performed in 27 (79%) patients, a palliative resection in 8 (18%) and one (3%) patient had a palliative colostomy only. Dukes' staging based on the worse of the 2 cancers showed 1 (3%) Dukes' A, 11 (32%) Dukes' B, 14 (38%) Dukes' C and 9 (27%) with disseminated disease. Age, sex and Dukes' staging did not differ significantly from those of patients with solitary cancers and prognosis was also not adversely affected.
Résumé
34 (4,1%) de 820 patients opérés de cancer colorectaux entre avril 89 et octobre 92 avaient des cancers synchrones. 20 (59%) étaient des hommes et 14 (41%) des femmes. L'âge moyen était de 69, 3 ans (25–89 ans). Les tumeurs synchrones étaient localisées dans le même segment ou les segments voisins du colon chez 24 (71%) des malades. Une résection curative a été réalisée chez 27 (79%) des patients, une résection palliative chez 8 (18%) et un malade (3%) a eu seulement une colostomie palliative. Le stade de Dukes du cancer le plus évolué des 2 montrait 1 (3%) Dukes A, 11 (32%) Dukes B, 14 (38%) Dukes C, et 9 (27%) avec une maladie disséminée. L'âge, le sexe et le stade de Dukes ne différaient pas significativement de ceux des patients qui avaient un cancer unique et le pronostic n'était pas pire.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Warren S, Gates O (1932) Multiple primary malignant tumours. Am J Cancer 16:1358–1414
Moertel CG, Bergen JA, Dockerty MB (1958) Multiple carcinomas of the large intestine. A review of the literature and a study of 261 cases. Gastroenterology 34:85–98
Diamenta M, Bacon HE (1966) Primary multiple malignancy of the colon and rectum: report of 230 cases. Dis Colon Rectum 9:441–446
Carlos R, Travieso J, Knoepp LF, Hanley PH (1972) Multiple adenocarcinomas of the colon and rectum. Dis Colon Rectum 15:1–6
Ekelund GR, Phil B (1974) Multiple carcinomas of the colon and rectum. Cancer 33:1630–1634
Hancock RJ (1975) Synchronous carcinoma of the colon and rectum. Am Surg 41:560–563
Heald RJ, Bussey HJR (1975) Clinical experience at St. Mark's Hospital with multiple synchronous cancers of the colon and rectum. Dis Colon Rectum 18:6–10
Appel MF (1976) Preoperative and postoperative colonoscopy for colorectal carcinoma. Dis Colon Rectum 19:664–666
Lasser A (1978) Synchronous primary adenocarcinomas of the colon and rectum. Dis Colon Rectum 21:20–22
Reilly JC, Rusin LC, Theuerkauf FJ (1982) Colonoscopy: Its role in cancer of the colon and rectum. Dis Colon Rectum 25:532–538
Pagana TJ, Ledesma EJ, Mittleman A, Nava HR (1984) The use of colonoscopy in the study of synchronous colorectal neoplasms. Cancer 53:356–359
Maxfield RG (1984) Colonoscopy as a routine preoperative procedure for carcinoma of the colon. Am J Surg 147:477–480
Bat L, Neumann G, Shemesh E (1985) The association of synchronous neoplasms with occluding colorectal cancer. Dis Colon Rectum 28:149–151
Lau KE (1992) Singapore Census of Population 1990, statistical release 1: Demographic characterics. Department of Statistics, Singapore
Rose B (1971) Multiple synchronous cancer of colon. Br J Clin Pract 25:507–510
Rami K, John PW (1986) Quintuple synchronous colon carcinoma: a report of 2 cases. J Surg Oncol 32:55–57
Herbst CA Jr, Sessions JT Jr, Lapis JL (1980) Fibreoptic colonoscopic examination in surgical patients with colorectal cancer. South Med J 73:548–554
Thorson AG, Christensen MA, Davis SJ (1986) The role of colonoscopy in the assessment of patients with colorectal cancer. Dis Colon Rectum 29:306–311
Nottle PD, Polglase AL, Hughes ESR, Mcdermott FT, Pihl EA, Price AB (1983) Synchronous carcinomas of the large intestine. Aust NZ J Surg 53:329–532
Sollenberger LL, Eisenstat TE, Rubin RJ, Salvati EP (1988) Is preoperative colonoscopy necessary in carcinoma of the colon and rectum. Am Surg 1988; 54:113–115
Nava HR, Pagana TJ (1982) Postoperative surveillance of colorectal carcinoma. Cancer 49:1043–1047
Wolff WI, Shinya H, Geffen A, Ozoktay S, DeBeer R (1975) Comparison of colonoscopy and the contrast enema in five hundred patients with colorectal disease. Am J Surg 129:181–186
Gruber R, Schein CJ, Gliedman ML (1970) The second colon cancer. A retrospective analysis of the value of extended colonic resection. Am J Surg 119:652–654
Lillehei RC, Wangensteen OH (1955) Bowel function after colectomy for cancer, polyps and diverticulitis. JAMA 15:163–170
Enker WE, Dragacevic S (1978) Multiple carcinomas of the large bowel: a natural experiment in etiology and pathogenesis. Ann Surg 187:8–11
Berson HL, Berger L (1945) Multiple carcinomas of the large intestine. Surg Gynaecol Obstet 80:75–84
Lockhart-Mummery HE, Heald RJ (1972) Metachronous cancer of the large intestine. Dis Colon Rectum 15:261–264
Welch JP (1981) Multiple colorectal tumours. An appraisal of natural history and therapeutic options. Am J Surg 142:274–280
Ottinger LW (1978) Frequency of bowel movements after colectomy with ileorectal anastomosis. Arch Surg 113:3–9
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Eu, K.W., Seow-Choen, F. & Goh, H.S. Synchronous colorectal cancer in an oriental population. Int J Colorect Dis 8, 193–196 (1993). https://doi.org/10.1007/BF00290304
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00290304