Abstract
A computer program based on the Monte Carlo technique was developed for calculation of absorbed dose rate in various tissues and organs. The accuracy of the program was tested by reproducing Berger's values of the specific absorbed fractions for point isotropic sources in water, and a good agreement with those obtained by the moments method was found within an error of several percent. In comparing with experiment and other Monte Carlo results, good agreement was also obtained within the range of statistical error. The absorbed dose rate for an 123I, 124I, 125I, 126I and 99mTc point source and their specific dose constants in various tissues and organs were calculated using this program. This computer program has the mass energy absorption and attenuation coefficients for 69 tissues and organs as a database file, and can be extended to various radionuclides used in nuclear medicine by adding their nuclear data to the program.
Similar content being viewed by others
References
Baker GA, Lum DJ, Smith EM, Winchell HS (1976) Significance of radiocontaminants in 123I for dosimetry and scintillation camera imaging. I Nucl Med 17:740–743
Berger MJ (1968) Energy deposition in water by photons from point isotropic sources. J Nucl Med [Suppl 1] 9:17–25
Burns GS, Raeside DE (1983) Monte Carlo estimates of specific absorbed fractions for an I-125 point source in water. Med Phys 10:197–198
Cromer DT (1974) Atomic scattering factors for x rays. International Tables for X-ray Crystallography (England) 4:71–147
Hanson HP, Herman F, Jea LD (1964) HFS atomic scattering factors. Acta Cryst 17:1040–1044
Hubbell JH (1975) Atomic form factors, incoherent scattering functions and photon scattering cross sections. J Phys Chem Ref Data 14:471–538
Hughes MH, Post DE (1978) A Monte Carlo algorithm for calculating neutral gas transport in cylindrical plasma. J Comput Phys 28:43–55
Ishine M, Murase K, Koizumi M, Itoh H, Kawamura M, Inatsuki S, Iio A, Yokoyama M, Yamamoto K, Hamamoto K (1982) Clinical values of renal function study with 123I-Orthoiodohippurate (123I-OIH). Kakuigaku 19:1483–1492
Loevinger R, Berman M (1976) A revised schema for calculating the absorbed dose from biologically distributed radionuclides, MIRD Pamphlet No. 1 Revised. The Society of Nuclear Medicine, New York
Meisberger LL, Keller RJ, Shalek RJ (1968) The effective attenuation in water of the gamma rays of Gold 198, Iridium 192, Cesium 137, Radium 226, and Cobalt 60, Radiology 90:953–957
MIRD/Dose estimate report No. 5 (1975) Summary of current radiation dose estimates to humans from 123I, 124I, 125I, 126I, 130I, 131I, and 123I as sodium iodide. J Nucl Med 16:857–860
Raeside DE (1976) Monte Carlo principles and applications. Phys Med Biol 21:181–197
Sherbini S, Schadt W, Thomas M, Alavijeh HS, Tripathi A (1979) A Monte Carlo computer code to calculate radiation dose from syringes containing radioactive substances. J Nucl Med 15:882–887
Storm E, Israel HI (1970) Photon cross sections from 1 keV to 100 MeV for elements Z=1 to Z=100. Nuclear Data Tables A7:565–681
Webb S, Fox RA (1979) The dose in water surrounding point isotropic gamma-ray emitters. Br J Radiol 52:482–484
White DR (1977) An analysis of the Z-dependence of photon and electron interactions. Phys Med Biol 22:219–228
White DR, Fitzgerald M (1977a) Calculated attenuation and energy absorption coefficients for ICRP Reference Man (1975) organs and tissues. Health Phys 33:73–81
White DR, Fitzgerald M (1977b) A tabulation of the 4th order polynomial coefficients calculated to fit the photon interaction data of 69 ICRP Reference Man tissues. Health Phys 33:628–633
Winchell HS, Baldwin RM, Lin TH (1980) Development of I-123-labeled amines for brain studies: localization of I-123 iodophenylalkyl amines in rat brain. J Nucl Med 21:940–946
Zerby CD (1963) A Monte Carlo calculation of the response of gamma-ray scintillation counters. In: Alder B, Fernbach S, Rotenberg M (eds) Methods in Computational Physics. Academic Press, New York, pp 89–134
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Murase, K., Kataoka, M., Yasuhara, Y. et al. Monte Carlo estimates of absorbed dose rate in various tissues and organs. Eur J Nucl Med 13, 109–114 (1987). https://doi.org/10.1007/BF00289020
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00289020