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Serumprotein polymorphisms in Iran

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Summary

The results of a population genetic investigation on Iranians are given and compared to the results obtained on other populations from Southwestern and Southern Asia. Our total material from Iran comprises n=1020 nonrelated male and female individuals of different age. The following serum groups have been typed: Hp, Gc, Gm, and Inv. In general there exist no remarkable age or sex differences in the distribution of phenotypes and alleles (the only exception: sex differences in the distribution of the Gm (7)-phenotype). The regional distribution of phenotypes and alleles yield no marked differences, too, apart from the Invphenotypes, however. For the total material of Iran the following alleles frequencies could be calculated: Hp1=0.3045, Hp2=0.6595, Gc2=0.3405; Gm1=0.1780, Gm1,2=0.0537, Gm1,5=0.0632, Gm5=0.7051. The Gm (7)-phenotype turned out to be 36.6%; the Inv (1)-phenotype amounts to 25.6%. Comparing with other populations, especially Pakistani and Indian samples, some heterogeneity in the distribution of phenotypes and alleles within Southwestern and Southern Asia was to be demonstrated. Some distributional trends of alleles frequencies shall be mentioned here: the increase of Hp2, Gc1, and Gm1 alleles from West towards East, and in the opposite direction the decrease of Hp1, Gc2, and Gm5 alleles. Selective acting forces are supposed to be most important factors for this.

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References

  • Cleve, H.: Die gruppenspezifischen Komponenten des menschlichen Serums. Heidelberg: Dr. A. Hüthig Verlag 1965.

    Google Scholar 

  • Kirk, R. L., and L. Y. C. Lai: The distribution of haptoglobin and transferrin groups in South and South East Asia. Acta genet. (Basel) 11, 97–105 (1965).

    Google Scholar 

  • — L. Y. C. Lai, G. H. Vos, and L. P. Vidyarthi: A genetical study of the Oraons of Chota Nagpur Plateau (Bihar, India). Amer. J. phys. Anthrop. 20, 375–385 (1962).

    CAS  PubMed  Google Scholar 

  • — H. Cleve, and A. G. Bearn: The distribution of the group specific component (Gc) in selected populations in South and South-east Asia and Oceania. Acta genet. (Basel) 13, 140–149 (1963).

    CAS  Google Scholar 

  • Podllachouk, L., A. Eyquem, R. Choaripour et M. Efterkhari: Les Facteurs Sériques Gm(a), Gm(b), Gm(x) et Gm-like chez les Iraniens. Vox Sang. (Basel) 7, 496–499 (1962).

    Google Scholar 

  • Ramot, B., P. Zikert-Duvevani, and G. Tauman: Distribution of haptoglobin types in Israel. Nature (Lond.) 192, 765–766 (1961).

    CAS  Google Scholar 

  • Ritter, H., C. Ropartz, P.-Y. Rousseau, L. Rivat u. H. Walter: Formale Genetik und Populationsgenetik des Inv-Polymorphismus. Blut 13, 373–377 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Ropartz, C., L. Rivat, P.-Y. Rousseau, R. Choaripour et M. Eftekhari: Répartition des groupes de gammaglobulines: Gm et InV chez les Iraniens. Acta genet. (Basel) 12, 45–50 (1962).

    CAS  Google Scholar 

  • —, P.-Y. Rousseau et L. Rivat: Hypothèses sur la Génétique Formelle du Système Gm chez les Caucasiens. Humangenetik 1, 483–496 (1965).

    Article  CAS  PubMed  Google Scholar 

  • Schultze, H. E., and J. F. Heremans: Molecular biology of human proteins with special reference to plasma proteins. Vol. I. Nature and metabolism of extracellular proteins. Amsterdam-London-New York: Elsevier Publ. 1966.

    Google Scholar 

  • Steinberg, A. G., L. Y. C. Lai, G. H. Vos, R. B. Singh, and T. W. Lim: Genetic and population studies of the blood types and serum factors among Indians and Chinese from Malaya. Amer. J. hum. Genet. 13, 355–371 (1961).

    CAS  PubMed  Google Scholar 

  • Vos, G. H., R. L. Kirk, and A. G. Steinberg: The distribution of the Gamma Globulin types Gm(a), Gm(b), Gm(x), and Gm-like in South and Southeast Asia and Australia. Amer. J. hum. Genet. 15, 44–52 (1963).

    CAS  PubMed  Google Scholar 

  • Walter, H.: Die Bedeutung der serologischen Merkmale für die Rassenkunde. 135–232. In I. Schwidetzky (Hrsg.): Die neue Rassenkunde. Stuttgart: Fischer 1962.

    Google Scholar 

  • — u. D. Djahanschahi: Zur Häufigkeit der Serumgruppen in Persien. Homo 14, 70–76 (1963).

    Google Scholar 

  • —, u. S. Neumann: Zur Häufikeit der Eigenschaft Gm(r) im südwestdeutschen Raum. Acta genet. (Basel) 15, 57–62 (1965).

    CAS  Google Scholar 

  • — W. Bernhard, S. Tahir Hassan u. M. Bajatzadeh: Untersuchungen über die Verteilung der Hp-, Gc- und Gm-Gruppen in Pakistan. Humangenetik 2, 262–270 (1966).

    CAS  PubMed  Google Scholar 

  • Walter, H. u. M. Bajatzadeh: Geschlechts-, Alters- und Regionalverteilung der Phänotypen InV (1) und InV (-1) in Persien. (In the press.)

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Authors and Affiliations

  1. Sektion Humangenetik, Anthropologisches Institut der Universität Mainz, Mainz, Germany

    Mansur Bajatzadeh & Hubert Walter

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  1. Mansur Bajatzadeh
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  2. Hubert Walter
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Bajatzadeh, M., Walter, H. Serumprotein polymorphisms in Iran. Hum Genet 6, 40–54 (1968). https://doi.org/10.1007/BF00287153

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  • DOI: https://doi.org/10.1007/BF00287153

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