Summary
A family pedigree is reported in which males in four generations are affected with midline isolated cleft palate. This is the second report of cleft palate inherited as a sex-linked recessive trait, and it emphasizes the importance of careful pedigree construction when counseling families of children afflicted with this disorder.
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Rushton, A.R. Sex-linked inheritance of cleft palate. Hum Genet 48, 179–181 (1979). https://doi.org/10.1007/BF00286901
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DOI: https://doi.org/10.1007/BF00286901