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Fragile chromosome 16(q22) cause a balanced translocation at the same point

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Summary

A father with a fragile 16(q22) has a son with a de novo balanced translocation 1;16. Both the fragile site and the break point at chromosome 16 are similar (q22).

The question of whether the fragile site can cause a structural chromosome abnormality at the same point is discussed.

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Authors and Affiliations

  1. Servicio de Genética Médica, C.E. Ramón y Cajal, Madrid, Spain

    J. M. García-Sagredo & C. San Román

  2. Sección de Endocrinologia Pediátrica, R.S. 1o de Octubre, Madrid, Spain

    M. E. Gallego Gómez & G. Lledo

Authors
  1. J. M. García-Sagredo
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  2. C. San Román
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  3. M. E. Gallego Gómez
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  4. G. Lledo
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García-Sagredo, J.M., San Román, C., Gallego Gómez, M.E. et al. Fragile chromosome 16(q22) cause a balanced translocation at the same point. Hum Genet 65, 211–213 (1983). https://doi.org/10.1007/BF00286668

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  • DOI: https://doi.org/10.1007/BF00286668

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