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The current state of research with peripheral tissues in Huntington disease

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Summary

Huntington disease is a neurological autosomal dominant disease of unknown origin and the search for a suitable diagnostic marker has been extended to the peripheral tissues. It is generally believed that a membrane defect exists in Huntington disease although the evidence is controversial. It is the aim of this review to examine the validity of these claims for each of the peripheral tissues and techniques involved, and it is not intended to include all other aspects of research into Huntington disease.

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  1. Department of Human Genetics, University of Leiden, Sylvius Laboratories, Wassenaarseweg 72, 2333 AL, Leiden, The Netherlands

    G. C. Beverstock

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Beverstock, G.C. The current state of research with peripheral tissues in Huntington disease. Hum Genet 66, 115–131 (1984). https://doi.org/10.1007/BF00286586

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