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Chromosomal breaks with attachments to the nucleolus

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Abstract

Among over 2,000 chromosomal aberrations produced by a cytoplasmic chromosome-breakage factor in Drosophila robusta, 28 have been unique in that the broken chromosome has become attached to the nucleolus. These have taken three forms according to the origin of the broken pieces. Particularly interesting are three aberrations of form 3 in which the chromosome attached to the nucleolus is an interstitial deletion. The data suggest that the nucleolus contains material with chromosome-like properties, particularly in possessing a centromere.

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Dedicated to a beloved teacher, Prof. Th. Dobzhansky, on his 70th birthday.

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Levitan, M. Chromosomal breaks with attachments to the nucleolus. Chromosoma 31, 452–467 (1970). https://doi.org/10.1007/BF00285836

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  • DOI: https://doi.org/10.1007/BF00285836

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