Abstract
Final concentration of 1% Scopolaminum hydrobromatum induced chromatid aberrations, but not reunion figures in HeLa cells. Duration of treatment was 5 hs, begin of treatment 22 resp. 46 hs before harvesting. In contrast to these findings no aberration was induced by Scop. hydr. in human leukocytes and BSC-K cells. It is concluded that mere findings in HeLa cells do not prove mutageneity of a chemical compound in man.
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Vrba, M. Chromosomenaberrationen, hervorgerufen durch Scopolaminum hydrobromatum. Hum Genet 4, 371–373 (1967). https://doi.org/10.1007/BF00285743
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DOI: https://doi.org/10.1007/BF00285743