Summary
dl-C-allylglycine inhibited the growth of Rd/3 sarcoma in male rats. The percentage tumor inhibition ranged from about 10–50 in a series of experiments carried out during an 18 month period.
dl-C-allyl-N-acetylglycine and the isomere l- and d-C-allylglycine also exhibited antitumor activity.
Zusammenfassung
dl-C-allylglycin hemmt das Wachstum des Rd/3 Sarkoms in männlichen Ratten. Während einer experimentellen Zeitspanne von 18 Monaten schwankte die prozentuelle Hemmung des Tumorwuchses zwischen 10% und 50%.
dl-C-allyl-N-acetylglycin und die Isomeren l- und d-C-allylglycin hemmen ebenfalls das Tumorwachstum.
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References
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Neish,W.J.P., Smith,J.A.: Inhibition of Rd/3 rat sarcoma by l-asparaginase alone and in combination with sodium para-aminosalicylate. Z. Krebsforschung 79, 78 (1973)
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Neish, W.J.P. Inhibition of Rd/3 rat sarcoma by dl-C-allylglycine. Z. Krebsforsch. 82, 295–300 (1974). https://doi.org/10.1007/BF00285564
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DOI: https://doi.org/10.1007/BF00285564