Summary
Amniocentesis was performed in a pregnancy of 26 weeks because of hydramnios. The amniotic fluid was examined for fetal karyotype and AFP content. The latter was elevated to 300 μg/ml. Fetal death occurred shortly after amniocentesis and a malformed male fetus with a large sacrococcygeal teratoma was stillborn 3 days later.
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Allan, L. D., Ferguson-Smith, M. A., Donald, I., Sweet, E. M., Gibson, A. A. M.: Amnioticfluid alpha-fetoprotein in the antenatal diagnosis of spina bifida. Lancet 1973 II, 522–525
Brock, D. J. H., Sutcliffe, R. G.: Alpha-fetoprotein in the antenatal diagnosis of anencephaly and spina bifida. Lancet 1972 II, 197–199
Gassner, M., Grob, P. J.: Alpha-1-Fetoprotein — diagnostische Bedeutung. Schweiz. med. Wschr. 104, 557–564 (1974)
Milunsky, A., Alpert, E., Charles, D.: Amniotic fluid alpha-fetoprotein in anencephaly. Obstet. and Gynec. 43, 592–594 (1974)
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Schmid, W., Mühlethaler, J.P. High amniotic fluid alpha-1-fetoprotein in a case of fetal sacrococcygeal teratoma. Hum Genet 26, 353–354 (1975). https://doi.org/10.1007/BF00285387
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DOI: https://doi.org/10.1007/BF00285387