Summary
Local X-ray irradiation of a transplantable rat tumour in a single dose of 3000 R increased significantly the extracellular space of this tumor as estimated by the plasma-tissue equilibration of 51Cr-EDTA, while the plasma and red blood cell volume as estimated with 125I-labelled albumin and 59Fe-labelled erythrocytes after sacrifice by bleeding under ether anaesthesia were unchanged. These results combined signified a decreased cell volume of cells, excluding red blood cells.
Zusammenfassung
Lokale Röntgenbestrahlung eines Rattentumores mit einer einmaligen Dosis von 3000 R vergrößerte signifikant den extracellulären Raum dieses Tumores, bestimmt durch die Plasma-Gewebeequilibrierung von 51Cr-EDTA. Das Volumen von Plasma und Erythrocyten war nach Tötung der Tiere durch Ausbluten unter Äther Anaesthesie-unverändert. Plasma wurde mit 125I-Albumin und Erythrocyten mit 59Fe markiert. Die Resultate zeigen ein reduziertes Zellenvolumen außer bei Erythrocyten.
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Peterson, H.I., Appelgren, L., Kjartansson, I. et al. Vascular and extravascular spaces in a transplantable rat tumour after local X-ray irradiation. Z. Krebsforsch. 87, 17–25 (1976). https://doi.org/10.1007/BF00285069
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DOI: https://doi.org/10.1007/BF00285069