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High incidence of the silent allele at cholinesterase locus I in Vysyas of Andhra Pradesh (S. India)

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Summary

Four-hundred and ninety individuals belonging to the Vysya caste from Andhra Pradesh were screened for pseudocholinesterase variants at the E1 and E2 locus. A high incidence of the silent allele (gene frequency = 0.1112) was recorded with homozygotes exceeding 2% of the population. Dibucaine- and fluoride-resistant alleles were found in a heterozygous form with the usual alleles in four individuals each. No C5+ variant at the E2 locus was found.

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Rao, P.R., Gopalam, K.B. High incidence of the silent allele at cholinesterase locus I in Vysyas of Andhra Pradesh (S. India). Hum Genet 52, 139–141 (1979). https://doi.org/10.1007/BF00284608

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  • DOI: https://doi.org/10.1007/BF00284608

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