Summary
V x 2-carcinomas were induced in rabbit femurs by various methods. Inoculation near the periosteum after injury of the condylus medialis femoris was considered most succesful. Results of 124 inoculations and 10 controls are demonstrated by angiograms, pharmakoangiograms and histologic photographs. Injury of periosteum and bone favors the taking and spreading of malignant growth.
Zusammenfassung
Im Femur von Kaninchen wurden mit verschiedenen Methoden V x 2-Carcinome erzeugt. Die Inokulation von Zellsuspension neben dem Periost nach Verletzung des medialen Oberschenkelknorrens erwies sich als erfolgreichstes Verfahren. Ergebnisse von 124 Fällen und 10 Kontrolltieren werden dargestellt mit Angiogrammen, Pharmakoangiogrammen und histologischen Bildern der Tumoren. Durch die Periostund Knochenverletzung wird das Übergreifen der Geschwülste auf den Knochen gefördert.
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Vargha, G., Miltényi, L., Endes, P. et al. Experimentelle Methode zur Erzeugung von V x 2-Knochentumoren bei Kaninchen. Z. Krebsforsch. 87, 161–171 (1976). https://doi.org/10.1007/BF00284373
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DOI: https://doi.org/10.1007/BF00284373