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Chemically induced esthesioneuroblastomas in rats

Induzierte Antifibrinolyse und intra-operative Aussaat von Tumorzellen

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Summary

Malignant tumours of the nasal cavity were induced in 19 of 56 (34%) female MRC-Wistar rats by 1-nitrosopiperazine administered orally for life. These tumours were of neurogenic origin, according to classical histologicriteria.

Zusammenfassung

Bösartige Geschwülste der Nasenhöhle wurden in 19 von 56 (34%) weiblichen MRC-Wistar-Ratten durch orale Gabe von 1-Nitrosopiperazin induziert. Nach histologischen Kriterien waren diese Tumoren neurogener Herkunft.

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Authors and Affiliations

  1. The Eppley Institute for Research in Cancer, University of Nebraska Medical Center, 42nd and Dewey Avenue, 68105, Nebraska, Omaha

    A. Pelfrene & H. Garcia

Authors
  1. A. Pelfrene
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  2. H. Garcia
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Supported by Public Health Service grant CA-05220-06 from the National Cancer Institute.

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Pelfrene, A., Garcia, H. Chemically induced esthesioneuroblastomas in rats. Z. Krebsforsch. 86, 113–119 (1976). https://doi.org/10.1007/BF00283998

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  • DOI: https://doi.org/10.1007/BF00283998

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