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Fragile sites and statistics

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Summary

A simple and reliable statistical method is proposed to distinguish real fragile sites from the casual accumulation of aberrations that can occur as a consequence of random distribution. It is based on a study of the expected random distribution, assumed to be equal to a Poisson distribution, with the expected value of events per band as the mean.

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Authors and Affiliations

  1. Istituto di Mutagenesi e Differenziamento C.N.R., Via Svezia, 10, I-56100, Pisa, Italy

    Tullio Mariani

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  1. Tullio Mariani
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Mariani, T. Fragile sites and statistics. Hum Genet 81, 319–322 (1989). https://doi.org/10.1007/BF00283683

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  • DOI: https://doi.org/10.1007/BF00283683

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