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Isolation and genetic analysis of temperature-sensitive mutants of B. subtilis defective in DNA synthesis

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Summary

Fifty temperature-sensitive mutants defective in DNA synthesis at high temperature have been identified among 655 temperature-sensitive mutants isolated at random from a mutagenised population of B. subtilis. They are distributed in a non-random fashion in 9 genetic linkage groups, located in different regions of the B. subtilis genome. It is suggested that at least 14 genes are involved in B. subtilis DNA replication.

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Communicated by W. Arber

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Karamata, D., Gross, J.D. Isolation and genetic analysis of temperature-sensitive mutants of B. subtilis defective in DNA synthesis. Molec. Gen. Genet. 108, 277–287 (1970). https://doi.org/10.1007/BF00283358

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  • DOI: https://doi.org/10.1007/BF00283358

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