Summary
The activity of the SOD Cu/Zn gene in balanced and unbalanced carriers of the 21/D and 21/G translocations is compared to that of subjects with free trisomy 21 and with normal karyotype. The results show that the translocation of the 21 chromosome has no effect on the activity of the SOD Cu/Zn gene.
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This work was supported in part by grant No. 500.6/49/1552 from the Ministry of Health
Recipient of a fellowship from the “Opera Sante de Sanctis”, Rome, for the education of the handicapped.
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Crosti, N., Rigo, A., Stevanato, R. et al. Lack of position effect on the activity of SODCu/Zn gene in subjects with 21/D and 21/G robertsonian translocations. Hum Genet 57, 203–204 (1981). https://doi.org/10.1007/BF00282023
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DOI: https://doi.org/10.1007/BF00282023