Abstract
Left ventricular myocardial mass can be measured by 201Tl SPECT, but the effects of changes in heart rate and contractility have not been determined. We constructed a dynamic computer model simulating the contracting left ventricle. Thirty two summed static views at each of 3 heart rates and 3 ejection fractions were manufactured to simulate a 180° acquisition. Each image set underwent tomographic reconstruction. Left ventricular mass was measured at a fixed percent threshold in each slice. The results show that left ventricular mass varied little with heart rate (4%) and only slightly more (8%) with ejection fraction. Thus, in the normal clinical setting, left ventricular mass measurements by SPECT are minimally affected by the dynamic state of the heart.
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Machac, J., Vaquer, R., Levin, H. et al. The effect of heart rate and contractility on the measurement of left ventricular mass by 201Tl SPECT. Eur J Nucl Med 13, 446–449 (1987). https://doi.org/10.1007/BF00281858
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DOI: https://doi.org/10.1007/BF00281858