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The genetic structure of the kuwaiti population II: The distribution of Q-band chromosomal heteromorphisms

Summary

The distribution of Q-band heteromorphisms in three Kuwaiti communities is reported. Of particular significance is the finding of large-Y segregating at a very high frequency (61.9%) in the Ajman tribesmen; and the absence of small-Y in the two tribal communities. The large variation in size of the Y-chromosome may reflect a unique cytogenetic feature of the inhabitants of the Arabian peninsula.

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References

  • Al-Nassar K (1979) The distribution of genetic markers and Q band chromosomal heteromorphisms in the Kuwaiti population. Ph. D. Thesis Indiana University

  • Al-Nassar K, Conneally PM, Palmer CG, Pao-lo Y (1981) The genetic structure of the Kuwaiti population: I. Distribution of 17 markers in the genetic distance analysis. Hum Genet 57:192–198

    Google Scholar 

  • Angell RR, Jacobs PA (1975) Lateral asymmetrie in human constitutive heterochromatin. Chromosoma 51:301–310

    Google Scholar 

  • Angell RR, Jacobs PA (1978) Lateral asymmetry in human constitutive heterochromatin: Frequency and inheritance. Am J Hum Genet 30:144–152

    Google Scholar 

  • Barker PE, Mohandas T, Kaback MM (1977) Chromsome polymorphisms in karyotypes from amniotic fluid cell cultures. Clin Genet 11:243–248

    Google Scholar 

  • Bochkov NP, Kuleshov NP, Chebotarev AN, Alekhin VI, Midian SA (1974) Population cytogenetic investigation of newborns in Moscow. Humangenetik 22:139–152

    Google Scholar 

  • Buckton KE, O'Riordan ML, Jacobs PA, Robinson JA, Hill R, Evans HJ (1976) C- and Q-band polymorphisms in the chromosomes of three human populations. Am Hum Genet 40:99–112

    Google Scholar 

  • Cohen MM, Shaw MW, MacCluer JW (1966) Racial differences in the length of the human Y chromosome. Cytogenetics 5:34–52

    Google Scholar 

  • Court Brown WM (1967) Human population cytogenetics, Amsterdam, North-Holland Publishing Co.

    Google Scholar 

  • Friedrich U, Nielsen J (1973) Chromosome studies in 5,049 consecutive newborn children. Clin Genet 4:333–343

    Google Scholar 

  • Geraedts JPM, Pearson PL (1974) Fluorescent chromosome polymorphisms: Frequencies and segregation in a Dutch population. Clin Genet 6:247–257

    Google Scholar 

  • Ghosh PL, Singh IP (1975) Morphological variability of the human chromosomes in two Indian populations—Rajputs and Punjabis. Humangenetik 29:67–78

    Google Scholar 

  • Hamerton JL, Ray M, Abbot A, Williamson CH, Ducasse GC (1972) chromosome studies in a neonatal population. Can Med Ass J 106:776–779

    Google Scholar 

  • Hamerton JL, Canning N, Ray M, Smith S (1975) A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities. Clin Genet 8:223–243

    Google Scholar 

  • Lin CC, Gedeon MM, Griffith P, Smink WK, Newton DR, Wilkie L, Sewell LM (1976) Chromosome analysis on 930 consecutive newborn children using quinacrine fluorescent banding technique. Humangenetik 31:315–328

    Google Scholar 

  • Lins LE, Sundequist U (1971) Y/E index in a Swedish population. Acta Genet Med Gemellol (Roma) 20:211–216

    Google Scholar 

  • Lubs HA, Ruddle FH (1970) Applications of quantitative karyotype to chromosome variation in 4,400 consecutive newborns. In: Jacobs PA, Apricet W, Law W (eds) Human population cytogenetics. Williams and Wilkins, Baltimore, pp 119–142

    Google Scholar 

  • Lubs HA, Ruddle FH (1971) chromosome polymorphisms in American Negro and White populations. Nature 233:134–136

    Google Scholar 

  • Lubs HA, Patil SA, Kimberling WJ, Brown J, Cohen M, Gerald P, Hecht F, Myrianthopoulos N, Summitt RL (1977) Q- and C-band polymorphisms in 7- and 8-year-old children: Racial differences and clinical significance. In: Hook EB, Porter IH (eds) Population cytogenetics: Studies in humans. Academic Press, New York, pp 133–159

    Google Scholar 

  • Magenis E, Palmer CG, Wang L, Brown M, Chamberlin J, Parks M, Merritt AD, Rivas M, Yu PL (1977) Heritability of chromosome banding variants. In: Hook FB, Porter IH (eds) Population cytogenetics: Studies in humans. Academic Press, New York, pp 179–188

    Google Scholar 

  • Magenis RE, Donlon TA, Wyandt HE (1978) Giemsa-11 staining of chromosome 1: a newly described heteromorphism. Science 202: 64–65

    Google Scholar 

  • McKenzie WH, Hostetter TL, Lubs HA (1972) Y family study: Heritable variation in the length of the human Y chromosome. Am J Hum Genet 24:686–693

    Google Scholar 

  • McKenzie WH, Lubs HA (1975) Human Q and C chromosomal variations: Distribution and incidence. Cytogenet Cell Genet 14: 97–115

    Google Scholar 

  • Mikelsaar AVN, Tuur SJ, Kaosaar ME (1973) Human karyotype polymorphisms. I. Routine and fluorescence microscopic investigation of chromosomes in a normal adult population. Humangenetik 20:89–101

    Google Scholar 

  • Mikelsaar AVN, Kaosaar ME, Tuur SJ, Viikmaa MH, Talvik TA, Laats J (1975) Human karyotype polymorphisms. III. Routine and fluorescence microscopic investigation of chromosomes in normal adults and mentally retarded children. Humangenetik 26:1–23

    Google Scholar 

  • Mikelsaar AVN, Ilus T, Kivi S (1978) Variant chromosome 3 (inv3) in normal newborns and their parents, and in children with mental retardation. Hum Genet 41:109–113

    Google Scholar 

  • Muller H, Klinger HP (1975) Chromosome polymorphism in a human newborn population. Part. I. In: Pearson PL, Lewis KR (eds) Chromosomes today, Vol 5. John Wiley and Sons, New York, pp 249–260

    Google Scholar 

  • Muller HJ, Klinger HP, Glasser M (1975) Chromosome polymorphisms in a human newborn population. II. Potentials of polymorphic chromosome variants for characterizing the idiogram of an individual. Cytogenet Cell Genet 15:239–255

    Google Scholar 

  • Nielsen J, Friedrich U (1972) Length of the Y chromosome in criminal males. Clin Genet 3:281–285

    Google Scholar 

  • Nielsen J, Sillesen I (1975) Incidence of chromosome aberrations among 11,148 newborn children. Humangenetik 30:1–12

    Google Scholar 

  • Nielsen J (1978) Large Y chromosome (Yq+) and increased risk of abortion. Clin Genet 13:415–416

    Google Scholar 

  • Oka S, Nakagome Y, Matusunaga E, Arima M (1977) LBA technique in the detection of chromosome variants. 10. Chromosomes with known sites of Q-variants. Hum Genet 39:31–37

    Google Scholar 

  • Paris Conference (1971) Standardization in human cytogenetics. Birth Defects: Original Article Series. VIII/7

  • Park J (1976) Human C-band polymorphisms: Frequency and distribution in Orientals. Ph. D. Thesis, Indiana University

  • Pearson PL, Bobrow M, Vosa CG, Barlow PW (1971) Quinacrine fluorescence in mammalian chromosomes. Nature 231:326–329

    Google Scholar 

  • Rivas ML, Conneally PM, Hecht F, Lovrien EW, Magenis E, Merritt AD, Meyers DA, Palmer CG, Wang L (1975) Linkage relationships of 1qh to Amy, Fy, PGM1 and Rh. Cytogenet Cell Genet 14:409–417

    Google Scholar 

  • Soudek D (1973) Chromosomal variants with normal phenotype in man. J Hum Evol 2:341–355

    Google Scholar 

  • Torre C de la, Gimenez-Martin G (1970) The human Y chromosome in the Spanish population. J Genet Hum 18:235–254

    Google Scholar 

  • Uchida IA (1973) Paternal origin of the extra chromosome in Down's syndrome. Lancet 2:1258

    Google Scholar 

  • Unnerus V, Fellman J, Chapelle A de la (1967) The length of the human Y chromosome. Cytogenet 6:213–227

    Google Scholar 

  • Verma RS, Lubs HS (1975) Variation in human acrocentric chromosomes with acridine orange reverse banding. Humangenetik 30: 225–235

    Google Scholar 

  • Zankl H, Zang KD (1971) Structural variability of the normal human karyotype. Humangenetik 13:160–162

    Google Scholar 

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Al-Nassar, K.E., Palmer, C.G., Conneally, P.M. et al. The genetic structure of the kuwaiti population II: The distribution of Q-band chromosomal heteromorphisms. Hum Genet 57, 423–427 (1981). https://doi.org/10.1007/BF00281697

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  • DOI: https://doi.org/10.1007/BF00281697

Keywords

  • Internal Medicine
  • Metabolic Disease
  • Genetic Structure
  • Arabian Peninsula
  • Tribal Community