Summary
In a study of spontaneous abortuses, the karyotype of 80 parental pairs were investigated in detail for chromosomal markers using Quinacrine-stained chromosome preparations from cultures of peripheral blood. Chromosomal markers were found in 26.9% of the parents and there was no difference between the frequency among parents of chromosomally abnormal and chromosomally normal abortuses.
Grouping of the markers in p+ or s+ and qh+ variants showed that there was a statistically significant difference between parents with karyotypically normal and abnormal abortuses, p+ and s+ variants being more frequent in the first and qh+ more frequent in the second group.
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Holbek, S., Friedrich, U., Lauritsen, J.G. et al. Marker chromosomes in parents of spontaneous abortuses. Hum Genet 25, 61–64 (1974). https://doi.org/10.1007/BF00281007
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DOI: https://doi.org/10.1007/BF00281007