Abstract
Two cases of chronic myelogenous leukaemia were studied during the final blastic crisis. The results show in case I a stemline of 50 (2 Ph1) intact and 2 fragmentary chromosomes, with a considerable variation from this mode, and in case II a stemline of 48 chromosomes (2 Ph1), with only a slight variation. Different aspects of the presentation of aneuploidy in CML are discussed in relation to the findings in both cases, and special attention is given to the formation of stemlines.
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Castro-Sierra, E., Gorman, L.Z., Merker, H. et al. Clinical and cytogenetic findings in the terminal phase of chronic myelogenous leukaemia. Hum Genet 4, 62–73 (1967). https://doi.org/10.1007/BF00279181
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DOI: https://doi.org/10.1007/BF00279181