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Dermatoglyphics in phenylketonuria

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Abstract

Dermatoglyphics of 100 phenylketonurics and 200 controls matched for ethnic origin and sex were compared. The present study of dermatoglyphics in phenylketonurics is consistent with results showing that single gene disorders have fewer and less striking anomalies of ridge development than diseases with gross chromosomal defects.

Analysis revealed a decreased frequency of whorl patterns on the finger tips and a wider mean summed atd angle among affected females as compared to normal females. The males showed no significant differences. Limited as they were to one sex, the differences seem unlikely to be attributable to the effect of the phenylketonuric gene.

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Authors and Affiliations

  1. Department of Neurology, Epidemiology & Genetics, Unit, Division of Neurology, University of Minnesota, Minneapolis, Minnesota

    Milton Alter

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  1. Milton Alter
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Additional information

This research was supported by the Minnesota Association for Retarded Children, The Graduate School of the University of Minnesota and United States Public Health Service Grant Number HD 01507-01.

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Alter, M. Dermatoglyphics in phenylketonuria. Hum Genet 4, 23–28 (1967). https://doi.org/10.1007/BF00279176

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  • DOI: https://doi.org/10.1007/BF00279176

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