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Linkage analysis of the Duffy blood group marker with several chromosome 1 genes in an extended pedigree with Charcot-Marie-Tooth disease

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Summary

We have recently demonstrated tight linkage of the Duffy blood group marker to the α-spectrin gene in an extended pedigree with Charcot-Marie-Tooth neuropathy. To determine a more precise location of the Duffy blood group locus on the chromosome 1 map we have tested several more chromosome 1 genes for linkage with this marker. We found suggestive linkage with the antithrombin III and apolipoprotein A2 genes and conclusive linkage with the gene coding for β-nerve growth factor.

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Raeymaekers, P., Van Broeckhoven, C., Backhovens, H. et al. Linkage analysis of the Duffy blood group marker with several chromosome 1 genes in an extended pedigree with Charcot-Marie-Tooth disease. Hum Genet 81, 231–233 (1989). https://doi.org/10.1007/BF00278994

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  • DOI: https://doi.org/10.1007/BF00278994

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