Summary
An inherited human karyological variant (14p+) has been studied with a number of cytochemical techniques. The short arm of this variant chromosome 14 is nearly as long as the long arm, giving the chromosome a submetacentric to metacentric appearance. In conventionally Giemsa-stained preparations, a maximum of three secondary constrictions can be observed in the marker arm. The secondary constrictions are silver-positive in Ag-NOR preparations. However, the entire arm stains deeply in N-banded preparations. The 14p+ arm also Q-negative, C-negative, G-negative, and R-positive with an almost homogeneous texture. The difference between N-banding and silver staining is interpreted as the result of gene activities of the ribosomal cistrons.
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Lau, Y.F., Wertelecki, W., Pfeiffer, R.A. et al. Cytological analyses of a 14p+variant by means of N-banding and combinations of silver staining and chromosome bandings. Hum Genet 46, 75–82 (1979). https://doi.org/10.1007/BF00278904
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DOI: https://doi.org/10.1007/BF00278904