Summary
The authors report the distribution of Gm- and Inv-groups in Hungary. In our total material of 378 males and females of different age, the frequency of the following Gm-phenotypes turned out: Gm (1, 2, 4, 5, 10)=4.1%, Gm(1,-2, 4, 5, 10)=25.3%, Gm(1,-2,-4,-5,-10)=3.4%, Gm(1, 2,-4,-5,-10)=0.4%, and Gm(-1,-2, 4, 5, 10)=66.8%. The alleles frequencies have been calculated to be Gm1=0.1622, Gm1, 2=0.0228, Gm4, 5, 10=0.8150. Observed and expected Gm-phenotypes frequencies are in good agreement under the assumption of the 3-alleles-model Gm1, Gm1, 2, Gm4, 5, 10. The Invphenotypes frequencies came out to be: Inv(1,-2)=0.5$, Inv(1,2)=8.2%, and Inv(-1,-2)=91.3%.
Among our Hungarian samples no significant differences were found, neither in the distribution of Gm-nor Inv-phenotypes and alleles. There exist no significant differences in the distribution of Inv-groups between our Hungarian sample and two German samples, but the Hungarian sample differs clearly from Czechoslovakian and Yugoslavian ones in the distribution of the Gm-phenotypes.
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References
Ritter, H., u. K. H. Drescher: Bestimmungstechnik der Gammaglobulin-Polymorphismen Gm und Inv.. Ärztl. Lab. 10, 88–97 (1964).
Ropartz, C., L. Rivat, P.-Y. Rousseau, H. Baitsch et J. van Loghem: Les Systèmes Gm et Inv en Europe Acta genet. (Basel) 13, 109–123 (1963).
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Ropartz, C., Rivat, L., Rousseau, P.Y. et al. Observations on the distribution of the Gm- and Inv-groups in Hungary. Hum Genet 5, 165–169 (1968). https://doi.org/10.1007/BF00278673
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DOI: https://doi.org/10.1007/BF00278673