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Genetic polymorphism of Isocitrate dehydrogenase in Primates

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Summary

The genetic polymorphism of isocitrate dehydrogenase has been investigated in 400 Primates. Six different phenotypes of the soluble enzyme were demonstrated. The mitochondrial enzyme exhibited a uniform electrophoretic pattern.

Zusammenfassung

Die Isocitratdehydrogenasen der Primaten zeigen eine genetisch determinierte Variabilität. Für das cytoplasmatische Enzym konnten 6 verschiedene Phänotypen nachgewiesen werden. Das mitochondriale Enzym verhielt sich in der Elektrophorese einheitlich.

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Reference

  • Chen, Shi-Han, Fossum, B. L. G., Giblett, E. R.: Genetic variation of the soluble form of NADP-dependent isocitric dehydrogenase in man. Amer. J. hum. Genet. 24, 325 (1972)

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Authors and Affiliations

  1. Institut für Anthropologie und Humangenetik, University of Tübingen, Jubingen, Germany

    J. Schmitt & H. Ritter

Authors
  1. J. Schmitt
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  2. H. Ritter
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Supported by the Deutsche Forschungsgemeinschaft.

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Schmitt, J., Ritter, H. Genetic polymorphism of Isocitrate dehydrogenase in Primates. Hum Genet 19, 327–329 (1973). https://doi.org/10.1007/BF00278412

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  • DOI: https://doi.org/10.1007/BF00278412

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