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Experimental study of ischemia time influencing free skin flap survival

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Summary

The relationship between the ischemia time of the isolated skin flap and its survival after transfer by microvascular anastomosis was studied in rat. Our result would confirm that warm ischemia of under 9 h will not adversely affect survival of transplanted skin flap while cool ischemia of under 48 h also will not have an adverse effect. Based on our histological findings, the degeneration of vessels and fatty tissue were the most important change in skin flaps resulting from ischemia.

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Torii, S., Harii, K. & Ohmori, K. Experimental study of ischemia time influencing free skin flap survival. Chir Plastica 4, 225–233 (1977). https://doi.org/10.1007/BF00277800

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