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Triplex gene dosage effect of TPI and G3PD in a human lymphoblastoid cell line with partial trisomy 12p13 and 18p

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Summary

The EBV-induced lymphoblastoid line established from a patient carrying a duplication of the distal part of chromosome 12 short arm (12p13) retained the original partial trisomy and displayed the same triplex gene dosage effect for TPI and G3PD as found in the patient's RBC and WBC.

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Authors and Affiliations

  1. Institut de Pathologie Moléculaire, 24, rue du Faubourg Saint Jacques, F-75674, Paris Cedex 14, France

    C. Junien & J. C. Kaplan

  2. Centre Régional de Transfusion Sanguine et d'Hématologie de Bordeaux, F-33035, Bordeaux Cedex, France

    F. Serville

  3. International Agency for Research on Cancer, 150, Cours Albert Thomas, F-69372, Lyon Cedex 2, France

    G. Lenoir

Authors
  1. C. Junien
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  2. J. C. Kaplan
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  3. F. Serville
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  4. G. Lenoir
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Junien, C., Kaplan, J.C., Serville, F. et al. Triplex gene dosage effect of TPI and G3PD in a human lymphoblastoid cell line with partial trisomy 12p13 and 18p. Hum Genet 49, 221–223 (1979). https://doi.org/10.1007/BF00277646

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  • DOI: https://doi.org/10.1007/BF00277646

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