Skip to main content
Log in

The arrangement of nucleotides in the coding regions of natural templates

  • Published:
Molecular and General Genetics MGG Aims and scope Submit manuscript

Summary

The relation of the nucleotide sequences in the coding regions of natural templates and of the short nucleotide sequence in 3′ terminus of 16 S ribosomal RNA was found to differ from random pattern. The observation is interpreted in terms of both the ribosomal interactions and the molecular evolution.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Berger, E.M.: Pattern and chance in the use of the genetic code. Jour. Molec. Evol. 10, 319–323 (1978)

    Google Scholar 

  • Bosch, L., Baan, R.A., van Boom, J.H., Caskey, C.T., van Dieijen, G., van Duin, J., Hilbers, C.W., van der Hofstadt, G.A.J.M., van Knippenberg, P.H., van der Laken, C.J., Naaktgeboren, N.: Structure and function of the 3′-terminus of 16S rRNA in relation to polypeptide initiation, elongation and termination. In: Translation of natural and synthetic polynucleotides (ed. Legocki, A.B.), Poznań (Poland) Publishers of Poznań Agricultural University 1977

    Google Scholar 

  • Chen, C.S., Nakamoto, T.: Translational specifity of Bacillus stearothermophilus ribosomes. Proc. Natl. Acad. Sci. 75, 161–171 (1978)

    Google Scholar 

  • Elton, R.A., Fiers, W.: Rhythmic variations in purine run frequencies in bacteriophage RNA. Jour. Theor. Biol. 63, 49–59 (1976)

    Google Scholar 

  • Ehresmann, Ch., Stiegler, P., Mackie, G.A., Zimmermann, R.A., Ebel, J.P., Fellner, P.: Primary sequence of the 16 S ribosomal RNA of Escherichia coli. Nucl. Acids Res. 2, 265–278 (1975)

    Google Scholar 

  • Fiers, W., Contreras, R., Duerinck, F., Haegeman, G., Iserentant, D., Merregaert, J., Min Jou, W., Molemans, F., Raeymaekers, A., van den Berghe, A., Volckaert, G., Ysebaert, M.: Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene. Nature 260, 500–507 (1976)

    Google Scholar 

  • Gottesman, M.E.: Reaction of ribosome-bound peptidyl-tRNA with aminoacyl-tRNA or puromycin. Jour. Biol. Chem. 242, 5564–5571 (1967)

    Google Scholar 

  • Heijne, G. von, Nilsson, L., Blomberg, C.: Translation and messenger RNA secondary structure. Jour. Theor. Biol. 68, 321–329 (1977)

    Google Scholar 

  • Sander, G.: Mechanism of action of colicin E 3. Effect on ribosomal elongation-factor-dependent reactions. Eur. J. Biochem. 75, 523–531 (1977)

    Google Scholar 

  • Sanger, F., Air, G.M., Barrel, B.G., Brown, N.L., Coulson, A.R., Fiddes, J.C., Hutchinson III C.A., Slocombe, P.M., Smith, M.: Nucleotide sequence of bacteriophage πX 174 DNA. Nature 265, 687–695 (1977)

    Google Scholar 

  • Sedláček, J., Rábry, M., Fychlík, I., Volný, D., Vítek, A.: Base pairing mRNA-rRNA. I. The arrangement of nucleotides in the message for coat protein of phage MS 2. Acta Virologica 22, 353–361 (1978)

    Google Scholar 

  • Shine, J., Dalgarno, L.: The 3′-terminal sequence of E. coli 16 S ribosomal RNA: Complementarity to nonsense triplets and ribosome binding sites. Proc. Natl. Acad. Sci. 71, 1342–1346 (1974)

    Google Scholar 

  • Sugimoto, K., Sugisaki, H., Okamoto, T., Takanami, M.: Studies on bacteriophage fd DNA. IV. The sequence of messenger RNA for the major coat protein gene. Jour. Molec. Biol. 111, 487–507 (1977)

    Google Scholar 

  • Springer, M., Grunberg-Manago, M.: Characteristics of N-Ac-Phe-tRNA binding and its correlation with internal aminoacyl-tRNA recognition. Biochem. Biophys. Res. Comm. 47, 477–484 (1972)

    Google Scholar 

  • Weissmann, C.: The making of a phage. FEBS Letters Supl. 40, 10–18 (1974)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Communicated by H.G. Wittmann

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sedláček, J., Fábry, M., Rychlik, I. et al. The arrangement of nucleotides in the coding regions of natural templates. Molec. Gen. Genet. 172, 31–36 (1979). https://doi.org/10.1007/BF00276212

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00276212

Keywords

Navigation