Skip to main content
SpringerLink
Log in

Satellite association in Down's syndrome

  • Original Investigations
  • Published:
Human Genetics Aims and scope Submit manuscript

Summary

The frequency of association of acrocentric chromosomes is examined in 20 Down's syndrome children, their parents, and 60 controls. Chromosome 21 enters into satellite associations most frequently, and chromosome 15 least. The parents of Down's syndrome children do not show any increased tendency for satellite association of chromosome 21 or indeed any other acrocentric.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Cohen MM, Shaw MW (1967) The association of acrocentric chromosomes in 1000 normal human male metaphase cells. Ann Hum Genet 31:129–137

    Article  Google Scholar 

  • Cooke P, Curtis DJ (1974) General and specific patterns of acrocentric association in parents of mongol children. Humangenetik 23:279–287

    CAS  PubMed  Google Scholar 

  • Cotton JE, Kaplan AR, Zsako S (1973) Acrocentric chromosomes in cultured leukocytes from mothers of children affected with the G1-trisomy syndrome. Am J Ment Defic 78:249–254

    CAS  PubMed  Google Scholar 

  • Curtis DJ (1974) Acrocentric associations in mongol populations. Humangenetik 22:17–22

    Article  CAS  Google Scholar 

  • Dittes H, Krone W, Bross K, Schmid M, Vogel W (1975) Biochemical and cytogenetic studies on the nucleolus organising regions (NOR) of man. Humangenetik 26:47–59

    CAS  PubMed  Google Scholar 

  • Hayata I, Oshimura M, Sandberg AA (1977) N-band polymorphism of human acrocentric chromosomes and its relevance to satellite association. Hum Genet 36:55–61

    Article  CAS  Google Scholar 

  • Henderson AS, Warburton D, Atwood KC (1973) Ribosomal DNA connectives between human acrocentric chromosomes. Nature 245:95–97

    Article  CAS  Google Scholar 

  • Hungerford DA (1965) Leucocytes cultured from small inocula of whole blood and the preparation of metaphase chromosomes by treatment with hypotonic KCL. Stain Technol 40:333–337

    Article  CAS  Google Scholar 

  • Jacobs PA, Mayer M, Morton NE (1976) Acrocentric chromosome associations in man. Am J Hum Genet 28:567–576

    CAS  PubMed  PubMed Central  Google Scholar 

  • Mattei JF, Mattei MG, Ayme S, Giraud F (1974) Etude chromosomique chez les parents d]enfants trisomiques 21. Association entre chromosomes acrocentriques. Humangenetik 25:29–48

    CAS  PubMed  Google Scholar 

  • Mattei JF, Ayme S, Mattei MG, Gouvernet J, Giraud F (1976) Quantitative and qualitative study of acrocentric associations in 109 normal subjects. Hum Genet 34:185–194

    Article  CAS  Google Scholar 

  • Mattevi MS, Salzano FM (1975) Effect of sex, age and cultivation time on number of satellites and acrocentric associations in man. Humangenetik 29:265–270

    Article  CAS  Google Scholar 

  • Mikkelsen M, Hansson A, Jacobsen P, Hobolch N (1975) Translocation (13q21q): four generation family study with analysis of satellite associations. Hum Genet 27:303–307

    CAS  Google Scholar 

  • Miller DA, Tantravahi R, Dev VG, Miller OJ (1977) Frequency of satellite association is correlated with amount of Agstaining of the nucleolus organizer region. Am J Hum Genet 29:490–502

    CAS  PubMed  PubMed Central  Google Scholar 

  • Phillips RB (1975) Inheritance of acrocentric association patterns. Humangenetik 29:309–318

    Article  CAS  Google Scholar 

  • Roberts DF, Callow MH (1980) The origin of the additional

Download references

Author information

Authors and Affiliations

  1. Department of Human Genetics, University of Newcastle upon Tyne, 19, Claremont Place, NE2 4AA, Newcastle upon Tyne, England

    E. V. Davison, D. F. Roberts & M. H. Callow

Authors
  1. E. V. Davison
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. F. Roberts
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. H. Callow
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Davison, E.V., Roberts, D.F. & Callow, M.H. Satellite association in Down's syndrome. Hum Genet 56, 309–313 (1981). https://doi.org/10.1007/BF00274685

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00274685

Keywords

Search

Navigation