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Expression in fibroblast culture of the satellited-X chromosome associated with familial sex-linked mental retardation

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Summary

The satellited-X chromosome previously shown in lymphocyte culture to be associated with certain types of sex-linked mental retardation has, for the first time, been demonstrated in cultured skin fibroblasts and lymphocytes from two affected males and an obligate carrier female. These findings provide a basis for reliable diagnosis of female carriers and for the development of prenatal diagnosis.

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Authors and Affiliations

  1. Department of Medical Genetics, James Mather Building, Faculty of Medicine, University of British Columbia, V6T 1W5, Vancouver, British Columbia, Canada

    P. B. Jacky & F. J. Dill

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  1. P. B. Jacky
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  2. F. J. Dill
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Jacky, P.B., Dill, F.J. Expression in fibroblast culture of the satellited-X chromosome associated with familial sex-linked mental retardation. Hum Genet 53, 267–269 (1980). https://doi.org/10.1007/BF00273509

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  • DOI: https://doi.org/10.1007/BF00273509

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